Application of hydroxypropyl betacyclodextrin in sertraline hydrochloride oral solution

Sertraline is selective serotonin recycle inhibitor (SSRI), the latest in a can help to improve the ability of the body, effectively alleviate the patient's depressive symptoms, including irritable mood, and can reduce the fatigue and anxiety state of sustainability, has a long-term, low poisonous to the cells of liver, the body clear, very suitable for the elderly taking etc., in the world has been widely used to treat depressive and obsessive-compulsive disorder.Compared with sertraline hydrochloride tablets, the oral liquid containing sertraline hydrochloride has the advantages of convenient taking, stable storage at low or normal temperature, fast absorption, good taste, more suitable for elderly patients, simple process and material saving.The present invention solves the sertraline hydrochloride oral liquid preparation technology on the key problem of solubility and stability problems, choose in the use of doses non-toxic excitant hydroxypropyl times he almost cyclodextrins and sugar mixture of lauric acid ester as solubilizer and stabilizer, which provides a with hydroxypropyl times he cyclodextrins and sugar mixture of lauric acid ester as solubilizer and stabilizer of sertraline hydrochloride oral solution. Shandong binzhou wisdom source biological technology co., LTD., is committed to specializing in the production of pharmaceutical excipients hydroxypropyl times he cyclodextrins and sodium sulfonated butyl times he cyclodextrin, has standard GMP management, advanced production equipment, professional team of experts, the sale of our products at the same time, also widely used in food, cosmetics, scientific research and other fields, you just need to, we just professional, welcome from all walks of life to come to visit.