Bisoprolol fumarate

Name: Bisoprolol fumarate
Availability: bisoprolol-fumarate-309566.html

Category:Active Pharmaceutical Ingredients
Product Name:Bisoprolol fumarate
CAS No.:104344-23-2
Standard:USP/ChP/BP/EP/JP
Price(USD):Negotiable
Company:Brother Enterprises Holding Co., Ltd

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Basic Info

Grade: pharmaceutical grade

Factory Location: JiangXi

Main Sales Markets: North America
Sample Provided: no

Bisoprolol Fumarate is the fumarate salt of a synthetic phenoxy-2-propanol-derived cardioselective beta-1 adrenergic receptor antagonist with antihypertensive and potential cardioprotective activities. Devoid of intrinsic sympathomimetic activity, bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, decreasing cardiac contractility and rate, reducing cardiac output, and lowering blood pressure. In addition, this agent may exhibit antihypertensive activity through the inhibition of renin secretion by juxtaglomerular epithelioid (JGE) cells in the kidney, thus inhibiting activation of the renin-angiotensin system (RAS). Bisoprolol has been shown to be cardioprotective in animal models.

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