Cytokines are small proteins (~5–20 kDa，also called peptides) important in cell signaling. They are involved in autocrine, paracrine, and endocrine signaling as immunomodulating agents. Cytokines include chemokines, interferons, interleukins, lymphokines, and tumor necrosis factors. They are important in immune responses to infection, inflammation, trauma, sepsis, cancer, and reproduction.
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