CERAMIDE 100403-19-8

Category:Active Pharmaceutical Ingredients
Product Name:CERAMIDE 100403-19-8
CAS No.:100403-19-8
Standard:In-house Standards
Price(USD):1.00
Company:Hangzhou Dingyan Chem Co., Ltd

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: hangzhou

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    CAS:100403-19-8 EINECS: 309-560-3

    appearance

    Light brown liquid

    smell

    Special cereal flavor

    PH

    4.5-6.5

    Density (g/ml)

    0.9000-1.3000

    Bacterial count (CFU/g)

    100 or less

    Pathogenic bacteria

    May not be detected

    Moisture content (%)

    95.0 or less

    barrier

    Grubauer et al. used acetone and other organic solvents to treat the skin of male hairless mice aged from 1 to 3 months to study the relationship between skin barrier function and skin lipids.

    Holleran et al. studied the relationship between epidermal barrier function and the synthesis of sphingolipids by infiltrating [3H]H20. The results showed that when the skin of hairless mice was treated with acetone to cause skin barrier dysfunction, the synthesis of sphingolipids increased. After 24 h, skin barrier function returned to normal, and nerve sheath lipid synthesis also returned to normal. Therefore, ceramides play an important role in maintaining skin barrier function.

    Adhere to

    Ceramides bind to proteins on the surface of cells by means of ester bonds, an interaction known as lipid-cell-protein encapsulation. Smith et al. have reported that the degree of adhesion between keratinocytes can be determined by the content of ceramide in the cuticle of the epidermis. The decrease of the content of ceramide in the cuticle of the epidermis can reduce the adhesion between keratinocytes, resulting in dry, desquamated and scaly skin.

    Pawlmgs et al. studied the desquamation mechanism of dry skin and found that the main cause of skin dryness was the decrease of ceramide content in the cuticle of the epidermis, and the content of ceramide was directly related to the degree of skin dryness. The use of ceramide can significantly enhance the adhesion between keratinocytes, improve the degree of skin dryness, reduce the phenomenon of skin descaling. Mary kay essence oil with this ingredient.

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