Daprodustat

Name: Daprodustat
Availability: daprodustat-312229.html

Category:Active Pharmaceutical Ingredients
Product Name:Daprodustat
CAS No.:960539-70-2
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Company:TianYuan Pharmaceutical Co.,Ltd.

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Basic Info

Grade: Pharmaceutical Grade

Factory Location: Zhongcheng Future Industrial Park, Hangcheng Avenue, Baoan District, Shenzhen

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa
Contract Manufacturing: CRO,CMO
Sample Provided: yes

Payment Terms: L/C

Daprodustat Biological Activity

Description:Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor being developed for the treatment of anemia associated with chronic kidney disease.

In Vitro:GSK1278863 is an orally administered small-molecule PHI, and stimulates endogenous EPO synthesis and induce effective erythropoiesis[1]. GSK1278863 has been shown to increase erythropoietin levels, leading to increases in hemoglobin, hematocrit and red blood cell numbers.

Density:1.4±0.1 g/cm3

Molecular Formula:C19H27N3O6

Molecular Weight:393.434

Exact Mass:393.189972

PSA:124.09000

LogP:0.86

Index of Refraction:1.580

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Daprodustat

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