DUTASTERIDE

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:DUTASTERIDE
CAS No.:164656-23-9
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Company:NIKSAN PHARMACEUTICAL

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: ANKLESHWAR , GUJARAT , INDIA

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa

  • Monthly Production Capacity: 100 KG

    Packaging Information: HDPE DRUM WITH LDPE INNER LINNR

  • Delivery Lead Time: IMMEDIATE

    Sample Provided: yes

    Payment Terms: L/C

    Niksan Pharmaceutical is an Ankleshwar based company who manufacture, supply, and export and distribute the very fine quality of Dutasteride API along with
    Dutasteride formulations. Our product Dutasteride is widely appreciated by our group companies and also by our clients. Niksan Pharmaceutical manufactures best quality product of Dutasteridein the best WHO GMP certified manufacture facilities. And provides all required documents of the drug we manufacture.

    Niksan Pharmaceutical export large quantity of the Dutasteride API and Dutasterideformulation worldwide since many years in countries like Myanmar (Burma), Lebanon, Sri Lanka, Singapore, Philippines, United Arab Emirates, Ireland, Pakistan, United Kingdom, India, Malaysia, Australia, Iraq, Lithuania, Jordan, Vietnam, Egypt, Bangladesh, Saudi Arabia, to 'Hong Kong, S.A.R., China' ,Netherlands, 'Taiwan, China', Latvia, Kenya, Hungary, Thailand, Slovakia, France, South Korea, Canada, Greece, Israel, Romania, New Zealand, Poland, United States, South Africa, Morocco, Belgium, Indonesia, Iran, Sweden, Italy, Germany, Turkey, Spain, Russia, Japan, Brazil and many more countries.

     

    Niksan Pharmaceutical manufacture and provides best quality of Dutasteride in all over Indian states like Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Madhya Pradesh, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka, Jammu and Kashmir, Kerala, Punjab, Rajasthan in large quantity.

     

    Dutasteride belongs to the medicine class called 5-alpha reductase inhibitor. Dutasteride used in the treatment of enlarged prostate. Dutasteride also used in the treatment of hair loss. Dutasteride used in a hormone therapy in the transgender women.

     

    SYNONYMS: Dutasteride, Dutasterida

     

    IUPACNAME: (1S,2R,7R,10S,11S,14S,15S)-N-[2,5-bis(trifluoromethyl)phenyl]-2,15-dimethyl-5-oxo-6-azatetracyclo heptadec-3-ene-14-carboxamide

     

    CAS NO: 164656-23-9

     

    MOLECULARFORMULA: C27H30F6N2O2

     

    MOLECLARMASS: 528.52 g/mol

     

    STORAGECONDITIONS: Store the medication in a room temperature. Put medication away from light and moisture. Keep medication away of reach of children and pet.

     

    HOWTOUSE:  Do not crush or chew the tablet, take whole tablet with water. Take the medicine orally with or without food. Use regularly to get more benefits.

     

    HOWDUTASTERIDEWORKS: Dutasteride is 5- alpha reductase inhibitor, Dutasteride works by blocking the synthesis of the natural substance which cause the enlargement of the prostate and give relief from it.

     

    PHARMACOKINETICS: Dutasteride absorbed rapidly after the oral administration. It takes 2-3 hours to reach the peak plasma concentration. Almost 99% of drug binds with the plasma proteins and 96.6% of drug binds with a-1 acid glycoproteins. The half-life of the drug is 5 weeks and remains in serum for 4-6 months.  The rout of elimination of the Dutasteride is by urination and by feces.

     

    PRECAUTIONS: Do not take the medicine if you are allergic to the Dutasteride or its residues.  Tell your doctor if you are using other medications. Tell your doctor if you have any heart, liver or kidney related problems. Do not donate blood after taking the medicine and for at least 6 month. This medication does not recommend for the females. Kindly avoid taking medicine if you are pregnant or breast feeding the baby.

     

    CDSCOAPPROVAL: Dutasteride capsules approved by CDSCO in India in 13.02.2004

    Combikit of Tamsulosin HCl 0.4mg M.R capsule (10 no.) & Dutasteride Soft Gelatine Capsule 0.5mg (10no.) approved by CDSCO in India in  19.01.2006

    Tamsulosin HCl (MR) 0.4mg + Dutasteride 0.5mg tablet approved by CDSCO in India in 06.02.2006

    Alfuzocin Hcl. ER (10mg) + Dutasteride 0.5mg tablet approved by CDSCO in India in 14.06.2007

     

    FORMULATIONSAVAILABLEINMARKET:

    Dutasteride 0.5 MG capsule

    Dutasteride 0.5 MG+Silodosin 8 MG tablet

    Dutasteride 0.5 MG+Silodosin 4 MG tablet

    Alfuzosin 10 MG+Dutasteride 0.5 MG tablet

    Tamsulosin 0.4 MG+Dutasteride 0.5 MG capsule

     

    Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

     

    REFERENCES:

    www.webmd.com

    https://pubchem.ncbi.nlm.nih.gov

    https://go.drugbank.com

    https://cdscoonline.gov.in

    https://www.wikipedia.org

    https://www.drugs.com

    https://www.zaubacorp.com

    https://www.practo.com/consult

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