FLUOCINOLONE ACETONIDE

Niksan Pharmaceutical is the largest manufacturer and exporter of the Fluocinolone Acetonideamong all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributor of the Fluocinolone AcetonideAPI and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceuticals are manufacturing and exporting large quantity of Fluocinolone Acetonidein all over the globe for many years in countries like 'Hong Kong, S.A.R., China', United States, Pakistan, India, Philippines, Indonesia, Italy, United Kingdom, Belgium, France, Algeria, Morocco, Netherland, Canada, united states, United Kingdom, Switzerland, Indonesia, Vietnam, Australia, Hungary, Finland, Turkey, Pakistan, Slovenia, Ireland, Zambia, Cyprus, Nigeria, Rwanda, South Africa, Denmark, Malawi, Croatia, Malta, Kazakistan, Slovenia, Bolivia, Japan, Uganda, Uzbekistan, Cameroon, Netherlands, Azerbaijan, Venezuela, Morocco, Cote D Ivoire, St Lucia, South Korea, Congo, Philippines, Colombia and Germany and my more countries.

Niksan Pharmaceutical provides Fluocinolone Acetonide to all states of India like Punjab, Rajasthan, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka, Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, and Madhya Pradesh etc.  We make all the formulations in the best WHO GMP certified field. We also give gift samples to the companies for R&D purpose.

Fluocinolone Acetonide comes in the topical steroid class IV. Fluocinolone Acetonide used in the treatment of many skin conditions like rash, irritation, eczema, dermatitis, redness of skin, swelling of skin etc.

SYNONYMS OF FLUOCINOLONE ACETONIDE:Acétonide de Fluocinolone, acetónido de fluocinolona, fluocinolon acetonid, Fluocinolone Acetonide, fluocinoloni acetonidum.

IUPAC NAME: (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacycloicosa-14,17-dien-16-one

CAS NO: 67-73-2

FORMULA: C24H30F2O6

MOLECULAR MASS: 452.495 g·mol−1

STORAGE CONDITIONS:Store in cool and dry place away from direct heat and moisture.Do not keep the container open for long time.Do not place in bathroom or any humid place.Keep away from children and pets.

HOW TO USE: Use the medication 3-4 times per day.Remember this medication is for external use only, do not consume it.Carefully wash and dry the part where the cream has to apply. Apply the medicine gently do not rub it.

HOW FLUOCINOLONE ACETONIDE WORKS:Fluocinolone acetonide is a corticosteroid. It can be inferred that it acts by inhibiting the fibroblast proliferation, edemacapillary dilation, leukocyte migration, fibrin deposition, capillary proliferation, collagen deposition, and scar formation on the body.

PHARMACOKINETICS: Fluocinolone Acetonide used for the sustain release. Fluocinolone Acetonide presents the sustain delivery action for straight 12 months.The systemic absorption of Fluocinolone Acetonide is very minor. The half-life of Fluocinolone Acetonide is around 1.3-1.7hours. Thus the systemic absorption is minimal Fluocinolone eliminate from kidney.

SIDE EFFECTS:The reactions like redness of skin, itching, burning, dryness of skin, irritation may see in patients. Tell your doctor if some serious side effects like stretch mark, skin rash, decolouration of skin, acne, or hair growth like effects appears.Notify your doctor if reddens swelling does not improve.Some rare side effects like rash, itching, swelling of skin, dizziness seen in the patients.

PRECAUTION:Before using the medication tell your doctor if you have any allergic reaction towards the Fluocinolone Acetonide.If you have problems like blood circulation problem, weak immunity or diabetes problem, do not use this medication.

Do not use the medication on face or in under arms.Fluocinolone Acetonide can effects on child’s growth if it given for the long time.

CDSCO APPROVAL: Fluocinolone acetonide approved by CDSCO in India August-1962

Hydroquinone 20mg + Tretinoin 0.25mg + Fluocinolone Acetonide 0.1mg per gm Cream approved by CDSCO in India 23.02.09.

FORMULATION AVAILABLE IN MARKET:

Fluocinolone Acetonide 0.01% w/w cream

Fluocinolone Acetonide 0.01%w/v solution

Fluocinolone Acetonide 0.01%w/w + Miconazole 2% w/w cream

Hydroquinone 20mg + Tretinoin 0.25mg + Fluocinolone Acetonide 0.1mg per gm Cream

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult