Heparin Sodium

Category:Intermediates > Pharmaceutical Intermediates
Product Name:Heparin Sodium
CAS No.:9041-08-1
Standard:USP, BP, EP, JP, In-house Standards
Company:Seebio Biotech (Shanghai) Co., Ltd.

Basic Info
  • Grade: Food Grade

    Factory Location: China

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: NA

    Packaging Information: NA

  • Delivery Lead Time: 10-30days

    Sample Provided: yes

    Payment Terms: TT; L/C;

    AHM0037A Heparin Sodium medicine grade CAS Number 9041-08-1;101921-26- Package: Function: prevent blood clotting , reduce blood fat,improve the coronary circulation Application: It has a wide range of uses in medicine Tags: Enrich the blood Anti Virus Blood lipid Regulation.

    Heparin sodium is the sodium salt of sulfated glycosaminoglycan, it is a mixture of different kinds of different molecular weight molecules, which can keep the activity of the composition to against different factor in blood clotting stage. It exists in mammals and usually be extracted from mammals of the intestinal mucosa or the right organization of the mammals which are feed by human.

     

    Heparin has strong anticoagulant effect, it is the primary drug choice to prevent deep vein thrombosis and thrombus diseases , although it has more than 60 years of history in clinic, but until now there is no substitutes can completely replace it, so it is still the most important biochemical drugs of anti coagulation and anti thrombosis.

    Raw material resource :Porcine intestinal mucosa

     

    Inspection items

    Specification

    Property

    White or off white powder, with strong hygroscopicity

    Identification

    Prolong the clotting time of complex calcium citrate sheep plasma

    NMR spectroscopy: complies

    HPLC:complies

    Complies the determination of sodium

    Inspection

    Clarity and color

    Clear and the staining degree is not over 5 chroma level of the control solution

    pH

    5.5~8.0

    Nucleotide impurity

    A260≤0.15

    Protein

    ≤0.5%

    Relative substance

    Complies

    N

    1.5%~2.5%(dry basis)

    Na

    9.5~12.5% (dry basis)

    Heavy metal

    ≤30 ppm

    Loss on drying

    ≤8.0%

    Bacterial endotoxin

    <0.01 IU each international units of heparin

    Valency

    ≥180 international units/mg (dry basis)

    Microbial test

    Total number of bacteria

    ≤103 /g

    Molds and yeast count

    ≤102 /g

    Intestinal bacteria and gram negative bacteria

    Not detected

    Escherichia coli

    Not detected

    Staphylococcus aureus

    Not detected

    Salmonella

    Not detected

    Storage: it should be stored in sealed container.

    Function:

     

    Common Heparin is a mixture containing a variety of amino dextran glucoside, it can delay or prevent blood clotting in vitro and in vivo. Heparin can reduce blood fat, decrease LDL and VLDL, increase HDL, changes blood viscosity, protect vascular endothelial cells, prevent atherosclerosis, promote blood flow, improve the coronary circulation.

     

    It has a wide range of uses in medicine, it can be used to treat viral hepatitis, acute myocardial infarction, it can increase the efficacy of hepatitis B if combined with RNA, it can assist to chemotherapy and prevent thrombosis, it also has effects on reducing blood fat and enhance the body's immune function.

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