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Category:Excipients > Solvents
Product Name:Hydroxypropyl-Beta-Cyclodextrin CAS 128446-35-5 Pharmaceutical grade hydroxypropyl betadex
CAS No.:128446-35-5
Standard:ChP, USP, EP
Price(USD):Negotiable
Company:Shandong Binzhou Zhiyuan Biotechnology Co., Ltd
Grade: Pharmaceutical Grade
Factory Location: Shandong China
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 300t
Packaging Information: 20kg/bag/drum
Delivery Lead Time: 2days
Sample Provided: yes
Payment Terms: L/L
Cyclodextrins are a family of compounds made up of sugar molecules bound together in a ring. Cyclodextrins are produced from starch by means of enzymatic conversion. They are used in food, pharmaceutical, drug delivery, and chemical industries, as well as agriculture and environmental engineering. Hydroxypropyl Beta Cyclodextrin is the chief active compound found in Procter and Gamble's deodorizing product "Febreze" under the brand name "Clenzaire".
Hydroxypropyl Beta Cyclodextrin is a prime candidate of all the chemically modified Cyclodextrins for incorporation into formulations used by humans and animals. HPBCD has the best balance of enhanced aqueous solubility, a wide range of drugs with which it forms stable complexes, and the most extensive collection of safety data in the technical literature with no adverse reactions reported. HPBCD is itself very soluble in water.
Basically used in solution to facilitate drug delivery.
ITEMS |
criteria |
|
Appearance |
White or almost white, amorphous or crystalline powder. Freely soluble in water and in propylene glycol. |
|
Identification |
IR |
Same absorption bands as USP Hydroxypropyl Betadex RS |
Clarity of Solution |
Positive |
|
Molar Substitution |
0.40~1.50 |
|
Betadex |
≤1.5% |
|
Propylene Glycol |
≤2.5% |
|
Any Other Single Impurity |
≤0.25% |
|
Total Impurities Excluding Betadex and Propylene Glycol |
≤1.0% |
|
Propylene Oxide |
≤0.0001% |
|
Loss on Drying |
≤10.0% |
|
Clarity of Solution |
1.0g/2ml water solution is clear and transparent |
|
Conductivity |
≤200µS/cm |
|
The total aerobic microbial count |
≤1000cfu/g |
|
The total combined moulds and yeasts count |
≤100cfu/g |
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