Linezolid

Appearance:

White Solid

Molecular Weight:

337.35

Density:

1.302 g/cm³

Boiling Point:

585.5 oC at 760 mmHg

Melting Point:

176-178oC

Flash Point:

307.9 oC

Storage Temperature:

Store in original container in a cool dark place.

Refractive index:

1.553

Solubility:

Insoluble

Biological Activity:

Oxazolidinone antibiotic. Inhibits bacterial protein synthesis prior to chain initiation. Displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo .

Usage:

Prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation.