MethylsulfonylMethane (MSM)

Products Description:

Methyl Sulfonyl Methane(MSM) is a naturally occurring, organic, sulfur-containing compound related to another sulfur-containing substance, dimethyl sulfoxide (DMSO). MSM is found in small amounts throughout nature and has been detected in small amounts in the blood and urine of humans.

FUNCTION:
 

Animal studies have shown that sulfur from oral supplements of MSM is incorporated into body proteins.2 Animal studies have also reported that joints affected by osteoarthritis (OA) have lower sulfur content,3 and mice with arthritis given MSM, experience less joint deterioration.4 According to a preliminary report, a double-blind trial in people with OA found that MSM, in the amount of 2,250 mg per day, reduced pain after six weeks.

According to some anecdotal reports, MSM has been used in human research for many years in amounts above 2000 mg per day with no significant adverse effects.7 However, diarrhea, skin rash, headache, and fatigue may be experienced in less than 20% of people, according to other anecdotal reports. Detectable levels of MSM in the brain of a person taking MSM supplements have been reported,8 but the significance of this finding, if any, is unclear.

At the time of writing, there were no well-known drug interactions with methylsulfonylmethane.

Some researchers have suggested that the resulting MSM could be responsible for the benefits attributed to DMSO. If so, MSM might be preferable as a treatment, because it does not cause some of the unpleasant side effects associated with DMSO treatment, such as body odor and bad breath. In addition, as a natural substance found in food, MSM would be expected to have a good safety profile.
 

SUGGESTED USE:
 

Some authorities report anecdotally that 250500 mg per day has beneficial effects on a variety of health problems.6 However, the only controlled trial using MSM used over 2000 mg per day to treat osteoarthritis. More research is needed before reliable recommendations for MSM supplementation can be made.