Terlipressin In-house Spec.

Terlipressin is a synthetic analogue of vasopressin used as a vasoactive drug in the management of hypotension. It is a prodrug, which is converted to (Lys8)- vasopressin after removal of the N-terminal triglycine in vivo. Terlipressin has a longer duration of action and a better safety profile than the parent compound.
Molecular Formula
C52H74N16O15S2
Molecular Weight
1227.37
Sequence
H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: 4-9)
Fields of application
Norepinephrine-resistant septic shock
Hepatorenal syndrome
Acute variceal hemorrhage (esophageal varices)