Trifluridine and Tipiracil Hydrochloride Tablets

【Ingredients】
This product is a compound preparation, the main ingredients are trifluridine and tepipyridine hydrochloride

Trifluridine

Chemical name: 2’-deoxy-5-(trifluoromethyl)uridine

Molecular formula: C10H11F3N2O5

Molecular weight: 296.20

Tepipyridine Hydrochloride

Chemical name: 2,4(1H,3H)-pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, hydrochloride (1:1)

Molecular formula: C9H11ClN4O2•HCl

Molecular weight: 279.12

Excipients: cellulose-lactose, crospovidone, magnesium stearate, film coating premix (gastric-soluble type).

【Properties】
This product is a white or off-white film-coated tablet, which appears white or off-white after removing the coating.

【Indications】
Have previously received fluoropyrimidine, oxaliplatin, and irinotecan-based chemotherapy, and have previously received or are not suitable for anti-vascular endothelial growth factor (VEGF) therapy, anti-epidermal growth factor receptor (EGFR) therapy (RAS Wild-type) patients with metastatic colorectal cancer (mCRC).

【Specification】    
(1) Each tablet contains 15mg of trifluridine and 7.065mg of tepipyridine hydrochloride

(2) Each tablet contains 20 mg of trifluridine and 9.420 mg of tepipyridine hydrochloride

[Usage and dosage] [Adverse reactions] [Taboo] [Precautions] Please refer to the instructions for details.