Spiolto® Respimat® enables greater physical activity in people living with Chronic Obstructive Pulmonary Disease

Boehringer Ingelheim announced data which add to the growing body of evidence that show Spiolto® (tiotropium/olodaterol) Respimat® enables greater physical activity in patients living with COPD. VESUTO® and OTIVATO® data were presented during the American Thoracic Society meeting (ATS) and PHYSACTO® data was recently published in the American Journal of Respiratory and Critical Care Medicine. (1,2,3)

Activity-related breathlessness is a characteristic feature of COPD.(5) It limits patients' exercise tolerance and has an impact on their daily activities, which can lead to a downward spiral of exercise avoidance and physical decline.(5,6) Decreased activity results in patients experiencing further breathlessness during even lower levels of physical activity, leading to further worsening of their condition, and increasing the risk of disability and death.(7) The internationally-recognised GOLD 2018 Strategy recommends maintaining or increasing physical activity for all COPD patients, regardless of disease severity.(4)

"It is of paramount importance that people with COPD remain as active as possible to minimise the impact of the disease on their daily lives," said Professor Thierry Troosters, Head of the Research Group for Cardiovascular and Respiratory Rehabilitation, University of Leuven, Belgium and principal investigator for the PHYSACTO® study. "The VESUTO®, OTIVATO®, and PHYSACTO® studies collectively show how tiotropium/olodaterol, a LAMA/LABA therapy, makes it easier for people with COPD to engage in physical activity by reducing symptoms and difficulty related to physical activity, thus improving their ability to exercise."

"Breathlessness is one of the hardest symptoms I deal with, but I try to do something active every day," said Simon Barson, who has been living with COPD for 10 years. "Even though I get myself extremely exhausted when I cycle or walk, I do it anyway because I know I'll get my breath back. I always feel better when I have exercised than when I have not."

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