Acetyl Chloride

Category:Intermediates > Chiral Intermediates
Product Name:Acetyl Chloride
CAS No.:75-36-5
Standard:ChP
Price(USD):Negotiable
Company:Nanjing Chemical Material Corp

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: China

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: Depend on the products

    Packaging Information: 200kg/drum

  • Delivery Lead Time: Depend on the products

    Sample Provided: yes

    Payment Terms: L/L

    Features of Acetyl Chloride

    • Product Name: Acetyl chloride
    • Chemical Formula: C2H3ClO
    • CAS No.: 75-36-5
    • Dangerous Grade: 3.2

    Technical Data of Acetyl Chloride

    ITERMS

    SPECIFICATION

    Appearance

    Colourless transparent liquid

    Assay

    ≥99.0%

    Phosphorus content

    ≤0.02%

     

    Package and Storage:

    • 200kg/drum
    • Store in a cool, dry place. Keep container closed when not in use

    Application /Application Industries:

    • Acetylation reagent
    • Pharmaceuticals
    • Dye

    Acetyl chloride is a colorless flammable liquid with a pungent odor. It is violently decomposed by water or ethanol. Dissolved in chloroform, ether, benzene, petroleum ether or glacial acetic acid. Acetyl chloride is an irritant and corrosive agent. Contact with the skin can cause burns, and steam can strongly irritate the eyes and mucous membranes. When people inhale 2 ppm, they can feel the stimulating effect. Short-term exposure to higher concentrations of acetyl chloride may cause death or permanent damage. The amount of aquatic live poisoning is estimated to be in the range of 10 to 100 ppm.

    Acetyl chloride is used for organic compounds, dyes and pharmaceuticals. Industrial acetyl chloride can be obtained by reacting ketene with hydrogen chloride or by reacting sodium acetate, sulfur dioxide and chlorine. The laboratory can be prepared by reacting acetic acid, sodium acetate or acetic anhydride with various chlorinating agents. Acetyl chloride is an important acetylating agent with a stronger acylation capacity than acetic anhydride and is widely used in organic synthesis. Acetyl chloride is also a catalyst for the chlorination of carboxylic acids and can also be used for the quantitative analysis of hydroxyl or amino groups.

    Acetyl chloride is an important organic synthesis intermediate and acetylation reagent. It has stronger acylation ability than acetic anhydride and is widely used in organic synthesis. It can be used in the production of pesticides, medicines, new electroplating complexes, and other fine organic synthesis. The intermediate can be used in medicine for the preparation of 2,4-dichloro-5-fluoroacetophenone (intermediate of ciprofloxacin), ibuprofen. Acetyl chloride is also a catalyst for the chlorination of carboxylic acids.

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