L-Glutathione Powder

Category:Active Pharmaceutical Ingredients
Product Name:L-Glutathione Powder
CAS No.:NA
Standard:In-house Standards
Price(USD):Negotiable
Company:Shaanxi Yuantai Biologicia technology Co. LTD

Basic Info
  • Grade: pharmaceutical grade

    Factory Location: Shanxi

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/C

    Product Description

     

    L-Glutathione powder (GSH) is a tripeptide consisting of glutamic acid, cysteine and glycine, and contains sulfhydryl groups. Glutathione (GSH) has antioxidant and integrated detoxification effects. The sulfhydryl group on cysteine is the glutathione active group (hence the glutathione is often referred to as g-SH), which is easy to combine with some drugs (such as paracetamol) and toxins (such as free radicals, iodoacetic acid, mustard gas, lead, , arsenic and other heavy metals), and thus has integrated detoxification effect. Thus, glutathione (especially glutathione in hepatocytes) is involved in biotransformation, which converts harmful toxins into harmless substances and excrete them out of the body. Glutathione also helps maintain normal immune system function

     

    We have ten years of experience in the field of plant extracts and cosmetic raw materials. We have our own factory, and for our cooperation to be more convenient and fast, we have set up branches in Europe and the United States, which can deliver faster and more favorable s price

    As a glutathione powder supplier(glutathione wholesale supplier), we supply pure glutathione powder (glutathione reduced powder). Regarding l glutathione powder, we can supply all products in the glutathione series. If you need wholesale glutathione, our initial cooperation may start with bulk glutathione , and all of our products support third-party testing.

    Test Report

     

    ITEM

    STANDARD

    TEST RESULT

    L-Glutathione

    98.0%~101.0%

    99.31%

    Physical & Chemical

       

    Appearance

     White crystalline powder

    Complies

    Solubility

    Soluble in water

    Complies

    Appearance of solution

    Clear and colorless

    Complies

    Loss on Drying

    ≤0.5%

    0.41%

    Optical rotation

    -15.5~-17.5°

    -16.5°

    Sulfate

    ≤0.03%

    Complies

    Chloride

    ≤0.02%

    Complies

    Ammonium(NH4)

    ≤ 0.02%

    Complies

    Total Related Substances

    ≤2.0%

    1.4%

    GSSG

    ≤1.5%

    0.4%

    Ash

    ≤0.1%

    0.06%

    Heavy Metal

       

    Total Heavy Metals

    ≤10ppm

    Complies

    As

    ≤2ppm

    Complies

    Pb

    ≤2ppm

    Complies

    Microbiological Test

       

    Total Plate Count

    ≤1,000cfu/g

    <100cfu/g

    Mold and Yeast

    ≤100cfu/g

    <10cfu/g

    E.Coli

    ≤10cfu/g

    <0.3cfu/g

    Salmonella

    Negative

    Negative

    Staphylococcus

    Negative

    Negative

    Conclusion

    Conform with specification

     

    Storage

    Store in cool and dry places. Keep away from strong light and heat.

     

    Packing

    By 25kgs/Drum, inner by double plastic bag

     

    Shelf Life

    24 months under the above condition,and in it’s original package

     

     

    Flow Chart

     

    L-Glutathione Flow Chart

    Analysis Report

     

    Glutathione Analysis Report

     

    Determination Of Content

     

    1.1 Instrument And Equipment

    High Performance Liquid Chromatography (HPLC)

    Chromatographic Work Station (N2010)

    1.2 The Condition Of Instrument

    Chromatographic Column: C18 150×4.6mm+ Guard Column

    Column Temperature: 29.8℃

    Flow Velocity: 0.8ml/min

    Detection Wavelength: 214nm

    Sample Amount: 20ul

    1.3 Reagent And Solution

    Trifluoroacetic Acid (TFA)

    Acetonitrile(CH3CN)

    Buffer Solution A: 0.1% TFA,H2O

    Buffer Solution B: 0.1%TFA,CH3CN

    Mobile Phase C: A:B=95∶5 (volume ratio)

    1.4 Test Methods

    Sample and reference material of Glutathione Reduced Accurately weigh 0.25g

    (accurate to 0.0002g) , add buffer A and dilute to 1000ml volumetric flask, and

    perform liquid chromatography analysis within half an hour.

    1.5 The Results Calculated

    The content X1 (expressed in weight percent) is calculated according to formula (1)

    Glutathione

    In the formula,

    A1—Sample absorption peak area,uv×s;

    A2—reference material absorption peak area,uv×s;

    m1—Weigh the sample in grams,g;

    m2—Weigh the reference material in grams,g;

    X2—Loss On Drying of sample,percentage by weight(%)

    Molecular Structure

     

    Glutathione

    Product Function

     

    Participate in redox reactions: as an important reducing agent, participate in a variety of redox reactions in the body

    Protect the activity of sulfhydrylase: keep the active group of sulfhydrylase—SH in a reduced state

    Maintain the stability of the red blood cell membrane structure: eliminate the damaging effect of oxidants on the red blood cell membrane structure

     

    As an important antioxidant in the body, glutathione can remove free radicals in the body

    L-Glutathione powder whitening skin: inhibit melanin

     

    Adding glutathione to food can play an unexpected role:

    1. Adding to noodle products can play a reducing role. It not only shortens the time for making bread to one-half or one-third of the original, but also greatly improves the working conditions, and plays a role in strengthening food nutrition and other functions.

    2. Add it to yogurt and baby food, which is equivalent to vitamin C, which can act as a stabilizer

    3. Mix it into the fish cake to prevent the color from deepening.

    4. Adding to meat products and cheese and other foods has the effect of intensifying flavor

     

    The whitening mechanism of glutathione:

     

    Glutathione powderReduced l glutathione powder can reduce tyrosinase activity in three different ways. Tyrosinase is directly inhibited by sulfhydryl chelating copper sites. Secondly, glutathione interferes with the cell transfer of tyrosinase to premelanosomes, which is a prerequisite for melanin synthesis. Third, the inhibition of tyrosinase is achieved indirectly through its antioxidant effect. Glutathione transfers melanogenesis from eumelanin to pheomelanin synthesis through the reaction between sulfhydryl and dopaquinone, resulting in the formation of sulfhydryl-dopa conjugates. Glutathione has a strong antioxidant capacity and has been proven to eliminate the reactive oxygen species produced in epidermal cells induced by ultraviolet radiation.

     

    Product Application

     

    Applied in the field of medicine, it can effectively treat various liver diseases

    Applied in the field of cosmetics, has an antioxidant effect, can delay aging

    Applied in the food field, it has a reductive effect in flour products, and has a role in enhancing flavor in meat products and dairy products

    Glutathione

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