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mPEG-DTA-4 (ALC-0159 Analog 4) is a polyethylene glycolated lipid (PEGylated lipid) that belongs to the structural analogs of the ALC-0159 series. It is widely used in lipid nanoparticle (LNP)-based drug delivery systems, particularly in the fields of mRNA vaccines and gene therapy. By optimizing the stability and biocompatibility of LNPs, mPEG-DTA-4 significantly enhances the delivery efficiency of nucleic acids (such as mRNA).