Mu-Conotoxin

What Are Conopeptides?

Mu-Conotoxin is a sorted, synthetic biological product that simulates conotoxin and has a very powerful muscle relaxation effect, allowing users to experience rapid and immediate anti-wrinkle effects. It is widely used in anti-wrinkle products. Conotoxins are highly folded peptides with strong penetration, high stability, and targeted muscle relaxation. By blocking neuromuscular current conduction, wrinkles are instantly reduced and the skin is rejuvenated and looks younger.
The cone snail is a venomous tropical marine mollusk and is said to be one of the 500 most venomous creatures in the world. Cono snails can produce polypeptide venom for predation and defense. Each conch venom of the conch family may contain up to 200 pharmacologically active ingredients. The cono peptides used in cosmetics are biologically simulated cono toxins that have been genetically sequenced and artificially Biomimetic synthesis preserves biological activity and efficacy while reducing most of the toxicity. The arginine/glutamine component in the ingredient list is conopeptide.

What Are The Benefits?

1. Developed by a Swiss laboratory with a background in biotechnology and drug research, it simulates neurotoxins, conotoxins. Biological effects: A nerve component relaxes muscles without paralyzing muscle activity.  Helps relieve wrinkles in a shorter period of time.

2. Conotide is a highly folded peptide with strong penetration, high stability, and targeted muscle relaxation. Conotide specifically blocks voltage-dependent sodium ion channels, specifically those in muscles. Conotoxin actually simulates the peptide component of conotoxin, so it is also called "conotoxin peptide" in some places. As reflected in the ingredient list, it is actually called "arginine/lysine peptide".

3. Arginine/lysine is shown in the ingredient list of cosmetics. It is the most popular anti-aging ingredient at the moment. The effect is very significant. It is called smear-type botulinum toxin. One application can last for 8 hours. Long-term Apply to reduce fine lines and delay skin aging. There are not many representative products on the market, and they are now popular in beauty salons.

5. Conotoxin has a relatively small molecular weight and extremely high target selectivity for voltage-gated channels. As a gated regulator of sodium ion channels, it can block voltage-dependent sodium channels for a long time, thereby regulating skeletal muscle expression, thus Achieve muscle relaxation and rapid and immediate anti-wrinkle effects.

6. Block sodium channels
From a mechanism point of view, conopeptide can inhibit the signal transmission of muscle contraction at multiple targets, retaining only 5% of neuromuscular current conduction, effectively relaxing the muscles without "paralyzing" the muscles, so it can provide a very natural and instantaneous Effect. Let's go directly to the verification of clinical data! After the subjects used 3% concentration of conopeptide, fine lines under the eyes were significantly reduced. The effect is already very significant in a short period of time (15 minutes), with an effective rate of up to 90%, and the effect lasts for 12 hours.

Principle Of Action

Mu-Conotoxin mainly acts on various ion channels, sodium ion channels, calcium ion channels, potassium ion channels and nicotinic acetylcholine receptors. Because of this, it is considered a potential "anti-wrinkle artifact."

It is a biomimetic peptide that is artificially synthesized after sorting and simulating the toxin secreted by cone snails in the laboratory. It is the smallest nucleic acid-encoded animal neurotoxin peptide found, and it is also the small peptide with the highest disulfide bond density. It can specifically block the current conduction of neurons in muscles, inhibit muscle contraction, thereby reducing wrinkles and making the skin anti-wrinkle.

It is worth mentioning that the blocking rate of conototide is >90%, and it retains part of the neuromuscular current transmission, which can avoid facial paralysis without making the skin too tight and stiff, thereby achieving natural removal. wrinkle effect. Studies have found that conopeptides can also relieve rhabdomyositis, and cosmetics based on conopeptides have also been developed to remove facial wrinkles.

At present, conotoxins used in the field of cosmetics mainly come from the μ family. Different μ-conotoxins can specifically act on different sodium ion channels. In particular, traditional μ-conotoxins can specifically block different sodium ion channels. Breaking the Nav 1.4 subtype of the sodium channel on skeletal muscle is widely used to eliminate wrinkles.

Advantage

On the market, the wrinkle removal effect is relatively fast and the effect is relatively significant. Its main ingredients are nothing more than botulinum toxins, such as acetyl hexapeptide-8. If acetyl hexapeptide-8 is a "big wrinkle remover", then Cono peptide is its "2.0" upgraded version and is the Mount Everest of peptides.
Conotoxin peptides are highly folded peptides with strong penetration, high stability, and targeted muscle relaxation.
Cono peptide has a strong immediate effect. Reports show that in a volunteer test, 3% cono peptide showed an obvious lightening effect within 5 minutes;

Using a skin tester, deep expression lines were significantly reduced in just two hours.
Conotide also has a very big advantage: it can provide effective muscle relaxation, but not complete stiffness and paralysis. Because it retains 5% of the neuromuscular current conduction of the muscles, it provides a natural wrinkle-removing and tightening effect.

Application

Conopeptide, known as the "wrinkle killer", can effectively inhibit muscle contraction and relax facial muscles, effectively removing wrinkles instantly.
Tests so far have not shown any cytotoxicity, skin irritation, allergy or eye irritation from conopeptides.
1. Conotoxins can be used in various anti-aging personal care products
2. Eye care: It can significantly remove eye wrinkles and crow's feet at the corners of the eyes.
3. Facial care: It can significantly remove wrinkles on the forehead caused by muscle contraction.

Company Introduction And Certificates Obtained

Founded in 2014, YTBIO mainly supplies food additives such as Mu-Conotoxin Powder, herbal extracts, functional cosmetic raw materials, organic products, etc. All of our products are produced by ourselves. At present, our certificates include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, etc. All our products have been tested and we support third-party testing. We provide a variety of products, for any detailed information about the products, please click Sales@Sxytbio.Com Contact us, we will have professional sales staff to give you detailed answers