Unique AutoPure - Protein purification system

Unique AutoPure-Protein purification system

The protein purification system is mainly used in the biopharmaceutical fields such as monoclonal antibody, recombinant protein, vaccines, biochemical drug, antibiotics, natural products and polysaccharides. Used for separation and purification of biological products in downstream process

Product Features and Advantages

· Modular design providing multiple configurations to meet special process requirements

· High-precision double plunger infusion pump with multiple patented technologies to ensure excellent separation reproducibility

· All parts of the whole system in contact with liquid are made of biocompatible materials, which meet the requirements of FDA, USP VI and other relevant laws and regulations

· DAD full spectrum direct reading detector to avoid the instability and high failure rate brought by the traditional mechanical grating detector

· The fixed wavelength detector lamp is a long-life LED lamp with a service life of more than 8000 hours, which ·reduces the maintenance cost

· Patented ultraviolet detector flow cell, with low dead volume and low peak expansion, which improves chromatography resolution

· High sensitivity on-line pH, conductivity and UV detector, low dead volume and low peak expansion, which improves chromatography resolution

· Centralized automatic components such as buffer selection valve, automatic sampling valve and column position valve, which improves the automation degree of purification

· Pre-column, post-column, differential pressure alarm and bubble sensor detection functions, which greatly protect the safety of the system and chromatography column

Unique CDsystem chromatography workstation software

Unique CDsystem is a powerful, advanced and stable chromatographic data management system

· CDsystem is integrates the functions of instrument control, method edit, evaluation, standard curve, report editing, user authority management, audit trial, electronic signature, network database etc

· CDsystem meets the requirements of FDA 21 CFR, Part 11 / GLP / GMP, and meets the requirements of the pharmaceutical industry for data traceability and safety

Product Model and Technical Parameters

· Standard configuration

Unique AutoPure Piston Pump

Unique AutoPure25

Piston Pump: Binary gradient biological inert infusion pump

Flowrate Range: 0.001-25ml/min

Gradient type: linear, isocratic, step gradient

Unique AutoPure100

Piston Pump:Binary gradient biological inert infusion pump

Flowrate Range: 0.001-100ml/min

Gradient type: linear, isocratic, step gradient

Unique AutoPure150

Piston Pump: Binary gradient biological inert infusion pump

Flowrate Range: 0.001-150ml/min

Gradient type: linear, isocratic, step gradient

Unique AutoPure300

Piston Pump:Binary gradient biological inert infusion pump

Flowrate Range: 0.01-300ml/min

Gradient type: linear, isocratic, step gradient

Automatic sampling valve

Controlled by software, supports Load/Inject/Waste

Fixed Wavelength Detector

LED, fixed single wavelength, optional 280nm, 260nm, or 254nm

Temperature Detector

Reading range: 0-100 ℃, temperature compensation for conductivity and pH

Conductivity Detector

Detection range: 0-999.999mS/cm, including temperature compensation

Back Pressure Valve Module

20psi (2ml/min)

Inline Filter Module

20μm titanium alloy filter

Control System

Unique CDSystem chromatography software (Without Computer)

· Optional Configuration

pH Detector

Detection range: pH 0-14, temperature compensation

Bubble sensor

Monitor sample loading and air bubbles in the system

UV detector

Fixed single wavelength, fixed dual wavelength, optional 2-4 wavelengths

Inlet Options

Both A/B pumps can be equipped with buffer inlets for 2, 6, 8, or 10 channels

Outlet Options

Optional with 2, 8, and 10 channel large volume outlets

Fraction Collectors

Multiple options such as open, closed, and temperature control fraction collectors

Column Valve

Single column valve, three column valve, including upflow and downflow

Pressure Sensor

System pressure, pre-column and post-column pressure

Sample Pump

Flowrate of 25, 100, 150, or 300ml/min, with optional inlets for 2, 6(only for 300 ml/min), 8, or 10 channels